• Adult Cardiac Arrest – VF/VTShockable pulseless cardiac arrest
• Air Embolism - VenousDecreased end-tidal CO2, decreased oxygen saturation, hypotension
• AnaphylaxisHypotension, bronchospasm, high peak-airway pressures, decreased breath sounds, tachycardia, urticaria
• Bradycardia – UnstableHR < 50 bpm with hypotension, acutely altered mental status, shock, ischemic chest discomfort, or acute heart failure
• Cardiac Arrest – Asystole/PEANon-shockable pulseless cardiac arrest
• Delayed EmergenceProlonged unresponsiveness following general anesthesia or abnormal neurologic exam following general anesthesia
• Failed Airway2 unsuccessful intubation attempts by an airway expert in a patient under general anesthesia
• FireEvidence of fire (smoke, odor, flash) on patient or drapes, or in patient’s airway, or in OR equipment
• HemorrhageAcute massive bleeding
• HypotensionUnexplained drop in blood pressure refractory to initial treatment
• HypoxiaUnexplained oxygen desaturation
• Local Anesthetic Systemic Toxicity (LAST)Neurologic or Cardiovascular Signs/Symptoms following use of local anesthetic
• Malignant HyperthermiaIn presence of trigger agent: unexpected, unexplained increase in end-tidal CO2, unexplained tachycardia / tachypnea,masseter muscle spasm after succinylcholine. Hyperthermia is a late sign.
• Myocardial IschemiaChest Pain, Shortness of Breath, ST Elevation or Depression, Ventricular Arrhythmias
• OB HemorrhageCumulative Blood Loss (intrapartum and postpartum) > 1000mL in vaginal or cesarean delivery or blood loss associated with signs or symptoms of hypovolemia within 24 hours after delivery
• Tachycardia - UnstablePersistent tachycardia with hypotension, ischemic chest pain, altered mental status, or shock
• Transfusion ReactionHemolytic Reaction: Cardiac instability, bronchospasm, bleeding, dark urineNon-hemolytic Reaction: fever, rash, pulmonary edemaAnaphylactic Reaction: hypotension, urticaria, bronchospasm