Air Embolism
PED-01
Diagnosis
Clinical diagnosis, may have:
- ↓ EtCO2
- ↓ SaO2
- ↓ BP
- mill-wheel murmur
More likely if surgical site above heart or air in IV line
Notify team
Stop nitrous oxide and volatile agents
Increase O2 to 100%
Stop air entrainment: find air entry point, stop source, and limit further entry
- Flood wound with irrigation/soaked saline dressing
- Turn off all pressurized gas sources: laparoscope, endoscope
- Place bone wax or cement on exposed bone edges
Check for open venous lines or air in IV tubing
Position surgical site below heart, head down, lateral if possible
Consider:
- Compress jugular veins intermittently if head or cranial case
Hemodynamic support if hypotensive:
- Give epinephrine 1-10 MICROgrams/kg, followed by infusion of epinephrine 0.02-1 MICROgrams/kg/min or norepinephrine 0.05-2 MICROgrams/kg/min
- Chest compressions: 100-120/min to force air through lock, even if not in cardiac arrest
- If available, call for Transesophageal Echocardiography/US
- Consider ECMO
Consider DDx
Crisis Management (If Severe)
Notify surgeon, call for help and code cart
Call for Transesophageal Echocardiography
Start chest compressions
Give epinephrine 10 MICROgrams/kg IV/IO
If cardiac arrest, go to CARDIAC ARREST
Consider ECMO
Drugs
| Epinephrine | 1-10 MICROgrams/kg IV/IO |
|---|---|
| Epinephrine | Consider infusion 0.02-1 MICROgrams/kg/min IV |
| Norepinephrine | Infusion 0.05-2 MICROgrams/kg/min IV |
Differential (Partial)
- Embolus: Fat, thrombotic, cement, amniotic fluid
- ANAPHYLAXIS
- LOCAL ANESTHETIC SYSTEMIC TOXICITY