Hypotension
PED-12
Diagnosis
Sustained low blood pressure with patient at risk for end-organ hypoperfusion, typically > 20% below baseline
Age · BP (mmHg)*
- Infant · MAP 30 or post-conceptual age in weeks
- 3 mo - 1 yr · 65 - 68 · < 5th% Systolic BP
- 1 - 3 yr · 68 - 74
- 4 - 12 yr · 70 - 85
- > 12 yr · 85 - 92
* Numbers are only a guide and vary for individual patients and situations
In pediatrics, hypotension is almost always treated by correcting hypovolemia or decreasing the anesthetic agent
Ensure oxygenation/ ventilation
Turn anesthetic agents down or off
Check cuff size and transducer position
If severe and/or persistent, consider placing arterial line if not already present
Etiology (Pick One):
Decreased preload
Expand circulating blood volume (administer fluids rapidly, consider PRBCs and albumin)
Trendelenberg position
Place or replace IV; consider intraosseous line
Causes: hypovolemia/HEMORRHAGE, vasodilation, impaired venous return, TAMPONADE, pulmonary embolism, hypocalcemia/blood product administration, IVC compression (prone, obese, surgical), pneumothorax/pneumoperitoneum, and increased PIP or PEEP
Decreased contractility
Start inotrope infusion, as needed
- Dopamine 2-20 MICROgrams/kg/min infusion IV
- Bolus epinephrine 1-10 MICROgrams/kg IV/IO, consider infusion 0.05-1 MICROgrams/kg/min IV
Consider Calcium chloride 10-30 mg/kg IV or Calcium gluconate 50 mg/kg IV
Review ECG for rhythm disturbances or ischemia
Send ABG, Hgb, electrolytes
Causes: negative inotropic drugs (anesthetic agents), arrhythmias, HYPOXIA, and heart failure (ISCHEMIA)
Decreased afterload
Start vasopressor infusion
- Consider infusion of norepinephrine 0.05-2 MICROgrams/kg/min IV
- Bolus phenylephrine 1-20 MICROgrams/kg IV/IO, consider infusion 0.1-2 MICROgrams/kg/min IV
Administer steroids for adrenal crisis
Causes: drug-induced vasodilation, sepsis, ANAPHYLAXIS, adrenal crisis, adrenal insufficiency, hypocalcemia, thyroid crisis
Crisis Management (If Severe)
Notify surgeon, call for help and code cart
Call for Transesophageal Echocardiography
Start chest compressions
Give epinephrine 10 MICROgrams/kg IV/IO
If cardiac arrest, go to CARDIAC ARREST
Consider ECMO
Drugs
| Calcium chloride | 10-30 mg/kg IV |
|---|---|
| Calcium gluconate | 50 mg/kg IV |
| Dopamine | Infusion 2-20 MICROgrams/kg/min IV |
| Epinephrine | Bolus 1-10 MICROgrams/kg IV/IO |
| Epinephrine | Consider infusion 0.05-1 MICROgrams/kg/min IV |
| Norepinephrine | Consider infusion 0.05-2 MICROgrams/kg/min IV |
| Phenylephrine | Bolus 1-20 MICROgrams/kg |
| Phenylephrine | Consider infusion 0.1-2 MICROgrams/kg/min IV |
Differential (Partial)
Differential Diagnosis: Pick One:
Decreased preload
- Hypovolemia/HEMORRHAGE
- Vasodilation
- Impaired venous return
- TAMPONADE, CARDIAC
- IVC compression (prone, obese, surgical)
- TENSION PNEUMOTHORAX/pneumoperitoneum/PE
- Increased PIP or PEEP
Decreased contractility
- Negative inotropic drugs (anesthetic agents)
- Arrhythmias
- HYPOXIA
- Heart failure (ISCHEMIA)
- Hypocalcemia/blood product administration
Decreased afterload
- Drug-induced vasodilation
- Sepsis
- ANAPHYLAXIS
- Adrenal crisis
- Hypocalcemia
- Thyroid crisis